Following the official signing of the Canada-United States-Mexico Agreement (CUSMA) during the G20 Leaders’ Summit in Buenos Aires in November 2018, the new agreement came into force on July 1, 2020. The CUSMA now replaces the North American Free Trade Agreement, which had been in place since 1994. At the time, NAFTA created the largest free-trade region in the world and shaped commercial activities on the continent. The far-reaching impact of the CUSMA will be felt in numerous fields of commercial activity and its implementation will take time. In terms of intellectual property, its effects are already noticeable.